Chapter 2 - Men and Monsters

Mission 1 - Mindless Mischief
Unlock Requirements:

Team Up: Destroyer, Elsa Bloodstone, Baron Mordo Location: Chinatown

Battles=

Minimum Score: 9
 * -|Heroic Battle=

Need: Dr. Strange, Doctor Voodoo

Team Up: Baron Mordo

Potential Reward: Invocating Empowered Isotope-8, Sorcerous Empowered Isotope-8, Thoughtful Empowered Isotope-8

Minimum Score: 4
 * -|Mini-Boss=

Team Up: Destroyer (Optional)

Minimum Score: 4

Team Up: Destroyer (Optional)

Minimum Score: 13
 * -|Boss=

Team Up: Elsa Bloodstone (Required)

Normal Mode Potential Reward: Mindless Eye, Hunter Augmented Isotope-8

Challenge Mode Potential Reward: Faltine Ring, Hunter Augmented Isotope-8


 * -|Deploys=

Minimum Score:
 * -|Epic Boss=

Team Up: Elsa Bloodstone (Required)

Normal Mode Potential Reward: Grave Spade, Valorous Augmented Isotope-8

Challenge Mode Potential Reward: Hell's Trigger, Valorous Augmented Isotope-8

Mission 2 - Speak of the Devil...
Unlock Requirements: Complete 3 Tasks

Team Up: Hellcat, Nightcrawler Location: Museum of Natural History

Battles=

Minimum Score: 9
 * -|Heroic Battle=

Need: Kitty Pryde, Magik

Potential Reward: Immaterial Empowered Isotope-8, Pneumatic Empowered Isotope-8

Minimum Score: 6
 * -|Mini-Boss=

Team Up: Hellcat (Optional)

Minimum Score: 6

Team Up: Nightcrawler (Optional)

Minimum Score: 13
 * -|Boss=

Team Up: Nightcrawler (Required)

Normal Mode Potential Reward: Hell's Contract, Vanishing Augmented Isotope-8

Challenge Mode Potential Reward: Brimstone Blade, Vanishing Augmented Isotope-8


 * -|Deploys=

Mission 3 - Dirty Hands
Unlock Requirements: Complete Complete 7 Tasks

Team Up: Vision,Victor Mancha Location: Ryker's Island


 * -|Battles=

Minimum Score: 4
 * -|Heroic Battle=

Need: Daredevil

Team-Up: Elektra

Potential Reward: Lawyered Empowered Isotope-8, Executing Empowered Isotope-8

Minimum Score: 3
 * -|Mini-Boss=

Team Up: Misty Knight(Optional)

Minimum Score: 10
 * -|Boss=

Team Up: Victor Mancha (Required)

Normal Mode Potential Reward: Cybernetic Helmet, Magnet A-Iso-8

Challenge Mode Potential Reward: Advanced Zapper, Magnet A-Iso-8

Minimum Cleared: All
 * -|Epic Boss=

Team Up: Victor Mancha (Required)

Normal Mode Potential Reward: Ghost Device, Magnet A-Iso-8

Challenge Mode Potential Reward: Ghost Prototype, Magnet A-Iso-8


 * -|Deploys=

Mission 4 - Kingpin of Crime
Unlock Requirements: Complete 11 Tasks

Team Up: Boomerang, Elektra Location: Chrysler Building


 * -|Battles=

Minimum Score: 7
 * -|Heroic Battle=

Need: Punisher

Team Up: Fixer

Potential Reward: Bulletproof E-Iso-8, Fixed E-Iso-8

Minimum Score: 5
 * -|Mini-Boss=

Team Up: Boomerang (Optional)

Team Up: Elektra (Optional)

Minimum Score: 13
 * -|Boss=

Team Up: Elektra (Required)

Normal Mode Potential Reward: Book of Martial Arts, Assassin A-Iso-8

Challenge Mode Potential Reward: Book of Advanced Martial Arts, Assassin A-Iso-8


 * -|Deploys=

Mission 5 - Big Deal
Unlock Requirements: Complete 15 Tasks

Team Up: Constrictor, Knight America Location: NY Public Library


 * -|Battles=

Minimum Score: 7
 * -|Heroic Battle=

Need: Quicksilver,Spitfire

Potential Reward: Light-Speed E-Iso-8

Minimum Score: 5
 * -|Mini-Boss=

Team Up: Constrictor (Optional)

Minimum Score: 13
 * -|Boss=

Team Up: Knight America (Required)

Normal Mode Potential Reward: Sword of America, Patriot A-Iso-8

Challenge Mode Potential Reward: Shield of America, Patriot A-Iso-8


 * -|Deploys=

{{Deploy|Generalist|1}

Mission 6 - Premium Mission: Zodiac
Unlock Requirements: Recruit Bulldozer

Team Up: A-Bomb, Bulldozer, (Heroic Battle) Location: Urban Core

Minimum Score: 7
 * -|Heroic Battle=

Need: Iceman

Team Up: Blizzard

Potential Reward: Cold Blood E-Iso-8, Cryogenic E-Iso-8

Minimum Score: 5
 * -|Mini-Boss=

Team Up: A-Bomb (Optional)

Minimum Score: 11
 * -|Boss=

Team Up: Bulldozer (Required)

Normal Mode Potential Reward: Zodiac Calendar, Bully A-Iso-8

Challenge Mode Potential Reward: Horn of Aries, Bully A-Iso-8

Minimum Cleared: All
 * -|Epic Boss=

Team Up: Bulldozer (Required)

Normal Mode Potential Reward: Butcher Knife, Bully A-Iso-8

Challenge Mode Potential Reward: Blueprint: Zodiac Key Prototype, Bully A-Iso-8


 * -|Deploys=

Chapter Mastery
Mastering the Chapter grants various rewards. The following heroes are required for chapter mastery.

Restricted Heroes
The following Heroes are unavailable due to mission restrictions.